Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 9/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10821929 | 0.86 | ALDH1A1 (0.39) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL10333508 | 0.84 | ALDH1A1 (0.38) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL588100 | 0.83 | ALDH1A1 (0.54) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL18789319 | 0.81 | ERN1 (0.37) | ALDH1A1ALOX15HSD17B10NR1I2LMNA | |
| SCHEMBL29111409 | 0.81 | ERN1 (0.56) | ERN1KDM4EPTGS2RAB9A | |
| SCHEMBL10806052 | 0.75 | CA2 (0.48) | ALDH1A1LMNATDP1TSHRCA2 | |
| SCHEMBL10940918 | 0.74 | TYR (0.41) | ALDH1A1ALOX15HSD17B10LMNATYR | |
| SCHEMBL311508 | 0.74 | GABRA1 (0.47) | ALDH1A1CYP2C9TYRERN1TDP1 | |
| SCHEMBL1093602 | 0.74 | CA2 (0.35) | ALDH1A1CYP2C9TYRERN1TDP1 | |
| SCHEMBL7717189 | 0.73 | ERN1 (0.49) | ALDH1A1ERN1TDP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101462072-B | Solid supported type metal schiff base catalyst and preparation method thereof | UNIV ZHENGZHOU | 2010-11-17 | — | — | CN | disclosed |
| CN-101462072-A | Solid supported type metal schiff base catalyst and preparation method thereof | UNIV ZHENGZHOU (CN) | 2009-06-24 | — | — | CN | disclosed |