SCHEMBL588100

SCHEMBL588100

CC(C)(C)c1cccc(O)c1C=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
TDP1 Q9NUW8 2/20 0.54
TSHR P16473 1/20 0.54
CA2 P00918 2/20 0.50
GABRA1 P14867 1/20 0.44
GABRB2 P47870 1/20 0.44
ERN1 O75460 5/20 0.41
ALOX12 P18054 1/20 0.41
HDAC4 P56524 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
CA1 P00915 1/20 0.39
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39
ALOX15 P16050 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
MAPT P10636 1/20 0.38
ATP2A2 P16615 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10806052 0.85 CA2 (0.48) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL27746643 0.83 ALDH1A1 (0.43) ALDH1A1TDP1TSHRCA2ERN1
SCHEMBL674140 0.80 ALDH1A1 (0.43) ALDH1A1TDP1TSHRCA2ERN1
SCHEMBL677594 0.80 NFKB1 (0.42) ERN1TRIM24TRIM33
SCHEMBL11772965 0.80 ALDH1A1 (0.54) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL311198 0.78 ERN1 (0.54) ALDH1A1TDP1CA2ERN1CA1
SCHEMBL19337408 0.78 GABRA1 (0.50) ALDH1A1TDP1TSHRCA2GABRA1
Tert-Butylbenzene SCHEMBL27403806 0.77 HDAC4 (0.50) ALDH1A1TDP1TSHRERN1HDAC4
SCHEMBL25532589 0.76 CA2 (0.40) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL16014567 0.76 ALOX15 (0.47) ALDH1A1TDP1TSHRCA2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 681 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115109541-A Tire crack repair composition and preparation method thereof 三角轮胎股份有限公司 2022-09-27 CN claimed
CN-114426741-A Preparation method of butyl rubber master batch, graphene-butyl rubber composition and preparation method and application of composite material of graphene-butyl rubber composition 中国石油化工股份有限公司 2022-05-03 CN claimed
CN-113955754-A Waste tire-based mesoporous carbon and preparation method thereof, rubber composition and preparation method and application thereof 赛轮集团股份有限公司 2022-01-21 CN claimed
CN-109476830-B Hardener composition and associated forming process, uncured and cured epoxy resin composition, and article 沙特基础工业全球技术有限公司 2021-07-09 CN claimed
CN-108290386-B Method of forming a cured epoxy material, cured epoxy material formed thereby, and composite core incorporating the cured epoxy material 沙特基础工业全球技术有限公司 2021-05-14 CN claimed
US-20190241698-A1 HARDENER COMPOSITION AND ASSOCIATED FORMING METHOD, UNCURED AND CURED EPOXY RESIN COMPOSITIONS, AND ARTICLE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-08-08 US claimed
CN-109476830-A Hardener composition and relevant manufacturing process, uncured and cured composition epoxy resin and product 沙特基础工业全球技术有限公司 2019-03-15 CN claimed
US-20180319930-A1 METHOD OF FORMING A CURED EPOXY MATERIAL, CURED EPOXY MATERIAL FORMED THEREBY, PHENYLENE ETHER OLIGOMER-ANHYDRIDE REACTION PRODUCT USEFUL IN THE METHOD, AND COMPOSITE CORE INCORPORATING THE CURED EPOXY MATERIAL SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-11-08 US claimed
CN-108290386-A It forms the method for cured epoxy material, the cured epoxy material formed by it, useful phenylene ether oligomer-anhydride reaction product and combine the composite material core of cured epoxy material in the method 沙特基础工业全球技术有限公司 2018-07-17 CN claimed
JP-4587669-B2 2010-11-24 JP claimed
EP-1443915-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES Cutanix Corporation (US) 2004-08-11 EP claimed
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments CUTANIX CORPORATION 2003-08-21 US claimed
WO-2003043621-A1 PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES CUTANIX CORPORATION (US) 2003-05-30 WO claimed
EP-0366020-B1 Desensitizing gum lithographic plate finisher FUJI PHOTO FILM CO LTD (JP) 1994-04-27 EP claimed
US-5128435-A Lubricants HITACHI, LTD. (JP) 1992-07-07 US claimed
EP-0275929-B1 COLOUR-DEVELOPING SHEET FOR PRESSURE-SENSITIVE RECORDING, AND COLOUR-DEVELOPING MATERIAL THEREFOR JUJO PAPER CO., LTD. (JP) 1991-08-07 EP claimed
US-4996135-A Applying water soluble starch modified with urea-phosphoric acid FUJI PHOTO FILM CO., LTD. (JP) 1991-02-26 US claimed
EP-0366020-A2 Desensitizing gum lithographic plate finisher FUJI PHOTO FILM CO., LTD. (JP) 1990-05-02 EP claimed
US-4076668-A COBALT SALT OF ORGANIC ACID, HYDROXYBENZOIC ACID THE YOKOHAMA RUBBER CO., LTD. (JA) 1978-02-28 US claimed
US-4060262-A Record material THE STANDARD REGISTER COMPANY (US) 1977-11-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments TYR, HRH1, HRH2 ALDH1A1 7/4885TDP1 498/4885TSHR 4382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.