Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.51 |
| ▸ | FPR2 | P25090 | 8/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27509445 | 1.00 | ALDH1A1 (0.59) | ALDH1A1PPARGPOLBPPARAGPR34 | |
| SCHEMBL1533645 | 0.88 | PPARG (0.58) | PPARGFPR2MMENPSR1 | |
| SCHEMBL1533647 | 0.88 | PPARG (0.58) | PPARGFPR2MMENPSR1 | |
| SCHEMBL6250861 | 0.88 | PPARG (0.58) | PPARGFPR2MMENPSR1 | |
| SCHEMBL71614 | 0.87 | MME (0.59) | PPARGFPR2ITGB1ITGA4MME | |
| SCHEMBL28789647 | 0.85 | PPARG (0.60) | PPARGFPR2MMENPSR1 | |
| SCHEMBL29166010 | 0.85 | PPARG (0.56) | PPARGFPR2ITGB1ITGA4MME | |
| SCHEMBL28789648 | 0.85 | PPARG (0.60) | PPARGFPR2MMENPSR1 | |
| SCHEMBL7100965 | 0.84 | PPARG (0.55) | PPARGFPR2ITGB1ITGA4MME | |
| SCHEMBL9843176 | 0.84 | ADAMTS5 (0.57) | PPARGPPARAGPR34FPR2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495502-A | N-terminally modified GLP-1 receptor modulators | BRISTOL MYERS SQUIBB CO (US) | 2009-07-29 | — | — | CN | claimed |
| CN-101282991-A | N-terminally modified GLP-1 receptor modulators | BRISTOL MYERS SQUIBB CO (US) | 2008-10-08 | — | — | CN | claimed |
| CN-101495502-A | N-terminally modified GLP-1 receptor modulators | BRISTOL MYERS SQUIBB CO (US) | 2009-07-29 | — | — | CN | disclosed |
| CN-101282991-A | N-terminally modified GLP-1 receptor modulators | BRISTOL MYERS SQUIBB CO (US) | 2008-10-08 | — | — | CN | disclosed |