SCHEMBL29166010

SCHEMBL29166010

Bc1ccc(N[C@@H](Cc2ccccc2)C(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.56
FPR2 P25090 9/20 0.51
MME P08473 1/20 0.50
NPSR1 Q6W5P4 1/20 0.49
NAALAD2 Q9Y3Q0 1/20 0.48
ITGB1 P05556 1/20 0.47
ITGA4 P13612 1/20 0.47
NPR3 P17342 1/20 0.47
CYP1A2 P05177 1/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1533647 0.90 PPARG (0.58) PPARGFPR2MMENPSR1NAALAD2
SCHEMBL1533645 0.90 PPARG (0.58) PPARGFPR2MMENPSR1NAALAD2
SCHEMBL6250861 0.90 PPARG (0.58) PPARGFPR2MMENPSR1NAALAD2
SCHEMBL71614 0.88 MME (0.59) PPARGFPR2MMEITGB1ITGA4
SCHEMBL28789647 0.87 PPARG (0.60) PPARGFPR2MMENPSR1NAALAD2
SCHEMBL28789648 0.87 PPARG (0.60) PPARGFPR2MMENPSR1NAALAD2
SCHEMBL27509445 0.85 ALDH1A1 (0.59) PPARGFPR2MMENPSR1ITGB1
SCHEMBL27746696 0.85 ALDH1A1 (0.59) PPARGFPR2MMENPSR1ITGB1
SCHEMBL9843176 0.85 ADAMTS5 (0.57) PPARGFPR2MMENPSR1MMP2
SCHEMBL7100965 0.85 PPARG (0.55) PPARGFPR2MMENPSR1ITGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117751409-A Method for optimizing protein production 英国研究与创新署 2024-03-22 CN disclosed
CN-117460698-A Surface-modified nanoparticles 国立大学法人京都大学 2024-01-26 CN disclosed