Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 2/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD5 | P21918 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisole SCHEMBL27747003 | 0.92 | ALDH1A1 (0.43) | ALDH1A1HSD17B10BCL9CTNNB1RAB9A | |
| Chlorobenzene SCHEMBL27747004 | 0.92 | BCL9 (0.39) | ALDH1A1HSD17B10BCL9CTNNB1DRD2 | |
| Fluorobenzene SCHEMBL27747012 | 0.92 | DRD2 (0.39) | ALDH1A1HSD17B10BCL9CTNNB1DRD2 | |
| 1,2-Dichlorobenzene SCHEMBL27747023 | 0.91 | ALDH1A1 (0.38) | ALDH1A1HSD17B10BCL9CTNNB1MAPT | |
| Ethylbenzene SCHEMBL27747179 | 0.91 | DRD3 (0.41) | ALDH1A1HSD17B10BCL9CTNNB1NPC1 | |
| SCHEMBL27768143 | 0.90 | DRD2 (0.37) | BCL9CTNNB1MAPTSMN1; SMN2DRD2 | |
| SCHEMBL28781337 | 0.86 | KMT2A (0.37) | BCL9CTNNB1MAPTDRD2DRD3 | |
| SCHEMBL3930618 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HSD17B10BCL9CTNNB1MAPT | |
| Anisole SCHEMBL27768025 | 0.85 | ALDH1A1 (0.44) | ALDH1A1BCL9CTNNB1RAB9ASMN1; SMN2 | |
| SCHEMBL3936397 | 0.84 | DRD2 (0.45) | ALDH1A1HSD17B10BCL9CTNNB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |