Asparagine

Asparagine

SCHEMBL27748103

CCCCN1C=CC=CC1.NC(=O)CC(N)C(=O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 4/20 0.39
SLC1A1 P43005 4/20 0.39
SLC1A3 P43003 3/20 0.39
GRIK1 P39086 7/20 0.36
GRIK2 Q13002 5/20 0.35
DDAH1 O94760 2/20 0.32
KIF11 P52732 1/20 0.32
GRIA4 P48058 1/20 0.31
GRIK3 Q13003 1/20 0.31
GRIK5 Q16478 1/20 0.31
LMNA P02545 1/20 0.31
NOS1 P29475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lysine SCHEMBL27727355 0.84 GSR (0.50) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
Bicarbonate SCHEMBL29505196 0.82 GBA2 (0.35)
Acetic Acid SCHEMBL28427571 0.80 GBA2 (0.34)
2-Ethylhexanoic Acid SCHEMBL29606937 0.77 CA2 (0.56) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
Acetic Acid SCHEMBL27735017 0.76 KCNH2 (0.32)
Lactic Acid SCHEMBL27658172 0.76 GPR84 (0.37)
Trifluoroacetic Acid SCHEMBL28736800 0.75 CPB2 (0.33)
Hydrochloric Acid SCHEMBL25225295 0.75 GBA2 (0.35)
Iodide SCHEMBL28474928 0.75 GBA2 (0.35)
Water SCHEMBL27754435 0.75 GBA2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101327450-A Aminoacid ion liquid carried Salen metallic catalyst and preparation method UNIV ZHEJIANG (CN) 2008-12-24 CN disclosed