Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4880922 | 0.78 | TSPO (0.45) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL3526000 | 0.75 | TSPO (0.52) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL4802524 | 0.72 | TSPO (0.48) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL3523645 | 0.71 | TSPO (0.56) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL19418868 | 0.71 | MAP2K4 (0.45) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL3590415 | 0.71 | TSPO (0.59) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL31339992 | 0.71 | TSPO (0.59) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL20171814 | 0.70 | HPGDS (0.36) | KMT2AMEN1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL10987170 | 0.70 | TSPO (0.58) | TSPOKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL15850566 | 0.70 | TSPO (0.61) | TSPOKMT2AMEN1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101429161-A | Synthesis of PET imaging agent prosome isoquinoline methanamide derivant | CHANGSHU INST TECHNOLOGY (CN) | 2009-05-13 | — | — | CN | disclosed |