SCHEMBL2774896

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9610551	0.93	ELANE (0.39)	ELANETHRBTDP1SLC6A1ALDH1A1
	SCHEMBL11964309	0.89	ELANE (0.35)	ELANETHRBTDP1SLC6A1ALDH1A1
	SCHEMBL9610344	0.84	SLC6A2 (0.38)	ELANEALDH1A1MAPTMEN1KMT2A
	SCHEMBL9610548	0.84	ELANE (0.39)	ELANEALDH1A1MAPTMEN1KMT2A
	SCHEMBL9610549	0.84	SLC6A1 (0.40)	ELANESLC6A1ALDH1A1MAPTMEN1
	SCHEMBL9610342	0.83	ELANE (0.34)	ELANETHRBTDP1ALDH1A1MAPT
	SCHEMBL9610334	0.83	ELANE (0.34)	ELANETHRBTDP1ALDH1A1MAPT
	SCHEMBL9610611	0.82	ELANE (0.38)	ELANEOPRM1OPRL1
	SCHEMBL9610607	0.82	ELANE (0.38)	ELANEMEN1KMT2AOPRM1OPRL1
	SCHEMBL29200195	0.82	THRB (0.38)	THRBTDP1SLC6A1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.