Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 7/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27727995 | 0.83 | METAP2 (0.42) | METAP2TACR1ACLYMETKIF11 | |
| SCHEMBL1768628 | 0.79 | PDE2A (0.40) | GABRA2GABRB2MAPTSMN1; SMN2GABRP | |
| SCHEMBL27926226 | 0.73 | GRM2 (0.52) | GABRA2GABRB2NPC1MAPTNFKB1 | |
| SCHEMBL28806082 | 0.73 | KIF11 (0.52) | METAP2NPC1MAPTNFKB1RAB9A | |
| SCHEMBL27749081 | 0.73 | PLK1 (0.38) | TACR1ACLY | |
| SCHEMBL28320613 | 0.72 | KIF11 (0.47) | METAP2TACR1MAPTKIF11BACE1 | |
| SCHEMBL2139259 | 0.72 | KIF11 (0.50) | METAP2TACR1GABRA2GABRB2ACLY | |
| SCHEMBL10280738 | 0.71 | GABRA2 (0.38) | GABRA2GABRB2MAPTSMN1; SMN2GABRP | |
| SCHEMBL7715418 | 0.71 | ALDH1A1 (0.47) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27720555 | 0.69 | METAP2 (0.50) | METAP2TACR1METKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101331124-B | Novel capsaicin receptor ligands and their use for the manufacture of medicaments | GRUENENTHAL GMBH | 2013-08-14 | — | — | CN | disclosed |
| CN-101331124-A | Novel capsaicin receptor ligands and their use for the manufacture of medicaments | GRUENENTHAL CHEMIE (DE) | 2008-12-24 | — | — | CN | disclosed |