Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | STK10 | O94804 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27749032 | 0.76 | HSD11B1 (0.46) | HSD11B1GPR3MAT2AALDH1A1KDM4E | |
| SCHEMBL9231954 | 0.71 | MEN1 (0.38) | GPR3ARMEN1KMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL28453942 | 0.70 | MEN1 (0.37) | GPR3ARALDH1A1MEN1KMT2A | |
| SCHEMBL6862522 | 0.69 | CYP2A6 (0.44) | HSD11B1CYP3A4CYP1A2DHODHALDH1A1 | |
| SCHEMBL1262778 | 0.69 | HSD11B1 (0.59) | HSD11B1ARCYP3A4ALDH1A1KDM4E | |
| SCHEMBL20329695 | 0.69 | TDP1 (0.41) | HSD11B1CYP3A4CYP1A2ALDH1A1KDM4E | |
| SCHEMBL28828302 | 0.68 | HSD11B1 (0.50) | HSD11B1GPR3ARALDH1A1KDM4E | |
| SCHEMBL9233334 | 0.68 | KIF11 (0.38) | GPR3ARMEN1KMT2AALOX15 | |
| SCHEMBL9232865 | 0.67 | KDR (0.35) | ARMEN1KMT2AALOX15MAPK1 | |
| SCHEMBL9281931 | 0.66 | APP (0.40) | ARCYP3A4CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101331124-B | Novel capsaicin receptor ligands and their use for the manufacture of medicaments | GRUENENTHAL GMBH | 2013-08-14 | — | — | CN | disclosed |
| CN-101331124-A | Novel capsaicin receptor ligands and their use for the manufacture of medicaments | GRUENENTHAL CHEMIE (DE) | 2008-12-24 | — | — | CN | disclosed |