Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MAT2A | P31153 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.40 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27727993 | 0.83 | MAT2A (0.43) | HSD11B1MAT2APDE2APDE10AALDH1A1 | |
| SCHEMBL28320613 | 0.79 | KIF11 (0.47) | MAT2AALDH1A1MEN1KMT2ATACR1 | |
| SCHEMBL1768902 | 0.78 | ALDH1A1 (0.54) | MCL1PDE2AALDH1A1MEN1KMT2A | |
| SCHEMBL27749079 | 0.76 | HSD11B1 (0.40) | HSD11B1MAT2ASTK10SLKALDH1A1 | |
| SCHEMBL31449901 | 0.76 | HSD11B1 (0.46) | HSD11B1MCL1PDE2APDE10ASTK10 | |
| SCHEMBL6862522 | 0.75 | CYP2A6 (0.44) | HSD11B1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL883518 | 0.74 | MCL1 (0.51) | MCL1ALDH1A1MAPTGAATRPV1 | |
| SCHEMBL28828302 | 0.73 | HSD11B1 (0.50) | HSD11B1MCL1PDE2APDE10ASTK10 | |
| SCHEMBL15714285 | 0.72 | KIF11 (0.50) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL19785385 | 0.71 | PDE2A (0.47) | HSD11B1MCL1PDE2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101331124-B | Novel capsaicin receptor ligands and their use for the manufacture of medicaments | GRUENENTHAL GMBH | 2013-08-14 | — | — | CN | disclosed |
| CN-101331124-A | Novel capsaicin receptor ligands and their use for the manufacture of medicaments | GRUENENTHAL CHEMIE (DE) | 2008-12-24 | — | — | CN | disclosed |