Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | RORB | Q92753 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28676412 | 0.82 | TSHR (0.56) | GPR3ARGLAGAAPOLB | |
| SCHEMBL1262778 | 0.81 | HSD11B1 (0.59) | HSD11B1ARGLAGAAKDM4E | |
| SCHEMBL31449901 | 0.77 | HSD11B1 (0.46) | HSD11B1GPR3ARRORCRORB | |
| SCHEMBL30239960 | 0.77 | GPR3 (0.45) | GPR3GLAGAAPOLBTSHR | |
| SCHEMBL11424977 | 0.77 | GPR3 (0.45) | GPR3ARGLAGAAPOLB | |
| SCHEMBL19785361 | 0.76 | PDE2A (0.52) | HSD11B1GPR3PDE2ATSHRALDH1A1 | |
| SCHEMBL15329536 | 0.76 | TSHR (0.47) | GLAGAAPDE2APOLBTSHR | |
| SCHEMBL28020022 | 0.76 | GPR3 (0.44) | HSD11B1GPR3GLAGAAPOLB | |
| SCHEMBL4781603 | 0.76 | KIF11 (0.54) | GPR3TSHRCES2ALDH1A1EDNRB | |
| SCHEMBL26374951 | 0.75 | GPR3 (0.42) | HSD11B1GPR3GLAGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884693-A | Parasiticidal Compositions Comprising Benzimidazole Derivatives, Methods And Uses Thereof | 梅里亚有限公司 | 2016-08-24 | — | — | CN | disclosed |