Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926221 | 0.81 | — | — | |
| SCHEMBL1810814 | 0.81 | SLC18A3 (0.48) | SLC18A3HTR6SLC6A4HRH1DRD2 | |
| SCHEMBL27770383 | 0.75 | DRD2 (0.43) | SLC18A3HTR6SLC6A4HRH1DRD2 | |
| SCHEMBL1814758 | 0.73 | SLC18A3 (0.70) | SLC18A3DRD2KDM1AALDH1A1 | |
| SCHEMBL2183515 | 0.73 | SLC18A3 (0.69) | SLC18A3DRD2KDM1A | |
| SCHEMBL27926225 | 0.69 | AOC1 (0.30) | — | |
| SCHEMBL21808291 | 0.69 | SLC18A3 (0.58) | SLC18A3DRD2ALDH1A1 | |
| SCHEMBL452972 | 0.68 | — | — | |
| SCHEMBL27832730 | 0.65 | NUDT1 (0.37) | — | |
| SCHEMBL3436371 | 0.65 | SLC18A3 (0.61) | SLC18A3HTR6SLC6A4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101432284-A | Dihydropyrazolopyrimidinone derivative | BANYU PHARMA CO LTD (JP) | 2009-05-13 | — | — | CN | disclosed |