Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RGS12 | O14924 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923849 | 0.83 | KDM4E (0.51) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL16027093 | 0.82 | CYP2C9 (0.58) | PTGESALOX5MEN1KMT2ARGS12 | |
| SCHEMBL9017573 | 0.76 | PLA2G2A (0.74) | MEN1KMT2ARGS12ALDH1A1LMNA | |
| SCHEMBL6820929 | 0.75 | KDR (0.46) | PTGESMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL4209387 | 0.75 | PTGDR2 (0.74) | PTGESALOX5MEN1KMT2ARGS12 | |
| SCHEMBL6821169 | 0.74 | KMT2A (0.52) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6025562 | 0.74 | MAPT (0.73) | PTGESALOX5MEN1KMT2ARGS12 | |
| SCHEMBL8649288 | 0.73 | AKR1C3 (0.51) | MEN1KMT2ARGS12ALDH1A1LMNA | |
| SCHEMBL13802435 | 0.73 | PTGDR2 (0.53) | PLA2G2AABCB1PTGDR2PPARG | |
| SCHEMBL9139483 | 0.72 | LMNA (0.76) | PTGESALOX5MEN1KMT2ARGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101360422-A | Oncogenic ras-specific cytotoxic compound and methods of usethereof | UNIV TEXAS (US) | 2009-02-04 | — | — | CN | disclosed |