Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CD74 | P04233 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820929 | 0.87 | KDR (0.46) | KMT2AALDH1A1MEN1TP53MAPT | |
| SCHEMBL6918963 | 0.84 | KDR (0.50) | KMT2AALDH1A1MEN1MAPTTSHR | |
| SCHEMBL6823481 | 0.84 | KMT2A (0.63) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL6920117 | 0.83 | CA12 (0.48) | KMT2ALMNAALDH1A1MEN1MAPT | |
| SCHEMBL6821059 | 0.83 | MAPT (0.48) | KMT2AALDH1A1MEN1MAPTMIF | |
| SCHEMBL6821058 | 0.83 | PLA2G2A (0.57) | KMT2AMAPTTSHRPLA2G2AMAPK1 | |
| SCHEMBL6820233 | 0.82 | CYP19A1 (0.59) | KMT2AALDH1A1MEN1MAPTPOLB | |
| SCHEMBL679026 | 0.80 | KMT2A (0.64) | KMT2ALMNAALDH1A1MEN1TP53 | |
| SCHEMBL22904941 | 0.77 | ESR1 (0.63) | ESR1 | |
| SCHEMBL6823487 | 0.76 | MDM2 (0.48) | KMT2AMEN1TP53MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |