Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918963 | 0.91 | KDR (0.50) | KDRMEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL6823487 | 0.88 | MDM2 (0.48) | KDRMEN1KMT2ATP53PTGES2 | |
| SCHEMBL6821169 | 0.87 | KMT2A (0.52) | MEN1KMT2AHTTTP53KDM4E | |
| SCHEMBL6820215 | 0.81 | KMT2A (0.52) | KDRMEN1KMT2AHTTPTGES | |
| SCHEMBL22904941 | 0.79 | ESR1 (0.63) | ESR1 | |
| SCHEMBL6821059 | 0.76 | MAPT (0.48) | MEN1KMT2AHTTHSD17B10KDM4E | |
| SCHEMBL6920117 | 0.76 | CA12 (0.48) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL6821058 | 0.76 | PLA2G2A (0.57) | KMT2AMAPTTSHR | |
| SCHEMBL27749337 | 0.75 | PTGES (0.59) | MEN1KMT2AHTTPTGES2PTGES | |
| SCHEMBL6820233 | 0.75 | CYP19A1 (0.59) | MEN1KMT2AHTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |