Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790160 | 0.89 | DPP4 (0.62) | DPP4POLBMAPTL3MBTL1NR1H2 | |
| Ammonia Solution, Strong SCHEMBL4267774 | 0.87 | DPP4 (0.60) | DPP4POLBMAPTL3MBTL1NR1H2 | |
| Ethane SCHEMBL27569819 | 0.85 | DPP4 (0.58) | DPP4POLBMAPTL3MBTL1CXCL8 | |
| SCHEMBL732827 | 0.83 | KMT2A (0.48) | KMT2AALDH1A1TDP1 | |
| SCHEMBL7176453 | 0.83 | DPP4 (0.53) | DPP4MAPTL3MBTL1CXCL8LMNA | |
| SCHEMBL10709985 | 0.81 | HTT (0.51) | KMT2A | |
| Diphenylether SCHEMBL130202 | 0.80 | LTA4H (0.67) | PGRNR1H2LMNAHPGDALDH1A1 | |
| SCHEMBL27474613 | 0.80 | FAAH (0.60) | MAPTLMNAGAAKMT2AHPGD | |
| SCHEMBL6299006 | 0.79 | POLB (0.49) | DPP4POLBMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL27749722 | 0.78 | PTGS2 (0.46) | POLBMAPTL3MBTL1NR1H2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101378757-A | Thiadiazole derivatives for the treatment of neuro degenerative diseases | REMYND NV (BE) | 2009-03-04 | — | — | CN | disclosed |