Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | WRN | Q14191 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27893994 | 0.83 | GABBR2 (0.40) | GABBR2GABBR1GSK3BWRNF2 | |
| SCHEMBL27708206 | 0.79 | GSK3B (0.36) | GSK3BWRNDAO | |
| SCHEMBL27586775 | 0.78 | ALOX5 (0.37) | DAO | |
| SCHEMBL27708354 | 0.78 | WRN (0.31) | WRN | |
| SCHEMBL27804136 | 0.75 | WRN (0.37) | WRN | |
| SCHEMBL1849742 | 0.75 | GABBR2 (0.39) | GABBR2GABBR1GSK3BWRNF2 | |
| SCHEMBL27894259 | 0.74 | LMNA (0.37) | GABBR2GABBR1 | |
| SCHEMBL7067216 | 0.72 | GABBR2 (0.40) | GABBR2GABBR1GSK3BWRNF2 | |
| SCHEMBL27616109 | 0.71 | — | — | |
| SCHEMBL4706414 | 0.71 | GABBR2 (0.39) | GABBR2GABBR1GSK3BWRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791714-A | N-(imidazopyrimidin-7-yl)-heteroarylamide derivatives and their use as PDE10A inhibitors | HOFFMANN LA ROCHE | 2012-11-21 | — | — | CN | disclosed |
| CN-102112474-A | Quinuclidine carbonate derivatives and medicinal composition thereof | CHIESI FARMA SPA | 2011-06-29 | — | — | CN | disclosed |
| CN-102056907-A | Heterocyclic derivative and use thereof | TAKEDA PHARMACEUTICAL | 2011-05-11 | — | — | CN | disclosed |
| CN-101511429-A | Indulines derivatives and gpr119 agonists | SMITHKLINE BEECHAM CORP (US) | 2009-08-19 | — | — | CN | disclosed |