Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1150157 | 0.84 | TSHR (0.46) | CES2ALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1150093 | 0.81 | LMNA (0.46) | CES2ALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1150260 | 0.80 | LMNA (0.47) | CES2ALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1150278 | 0.79 | CES2 (0.42) | CES2ALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1149784 | 0.79 | LMNA (0.59) | CES2ALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1685670 | 0.79 | PDCD1 (0.42) | CES2ALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1150579 | 0.78 | ALDH1A1 (0.43) | CES2ALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1150160 | 0.78 | LMNA (0.50) | ALDH1A1LMNATSHRCYP1A2CYP2C19 | |
| SCHEMBL1150127 | 0.77 | TDP1 (0.51) | ALDH1A1LMNATSHRCYP1A2CYP2C19 | |
| SCHEMBL1150535 | 0.76 | TDP1 (0.50) | ALDH1A1LMNATSHRTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101506142-A | Process for production of trans-2,2-dimethyl- 3-formylcyclopropane carboxylic acid ester | SUMITOMO CHEMICAL CO (JP) | 2009-08-12 | — | — | CN | disclosed |