Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1150093 | 0.87 | LMNA (0.46) | TSHRALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1150260 | 0.87 | LMNA (0.47) | TSHRALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1150278 | 0.85 | CES2 (0.42) | TSHRALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1685670 | 0.85 | PDCD1 (0.42) | TSHRALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1149784 | 0.85 | LMNA (0.59) | TSHRALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL27752185 | 0.84 | CES2 (0.40) | TSHRALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1150160 | 0.84 | LMNA (0.50) | TSHRALDH1A1LMNATDP1MAPK1 | |
| SCHEMBL1150579 | 0.84 | ALDH1A1 (0.43) | TSHRALDH1A1LMNACHRNB2CHRNA5 | |
| SCHEMBL1150245 | 0.83 | CHRNB2 (0.45) | ALDH1A1LMNACHRNB2CHRNA5CHRNA7 | |
| SCHEMBL1150127 | 0.83 | TDP1 (0.51) | TSHRALDH1A1LMNATDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341042-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2019-03-20 | — | — | EP | disclosed |
| CN-103958533-B | Optically active bisoxazoline compound, asymmetric catalyst, and method for producing optically active cyclopropane compound using same | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2016-02-10 | — | — | CN | disclosed |
| EP-1783111-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2015-04-08 | — | — | EP | disclosed |
| EP-2781522-A1 | OPTICALLY ACTIVE BISOXAZOLINE COMPOUND, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND USING SAID CATALYST | Sumitomo Chemical Company, Limited (JP) | 2014-09-24 | — | — | EP | disclosed |
| CN-1852887-B | Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same | SUMITOMO CO LTD | 2012-08-15 | — | — | CN | disclosed |
| EP-1950208-B1 | PROCESS FOR PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE | SUMITOMO CHEMICAL CO (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-7928253-B2 | Method of producing 6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7893294-B2 | Process for production of trans-2, 2-dimethyl-3-formylcyclopropanecarboxylic acid ester | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-22 | — | — | US | disclosed |
| US-20100168463-A1 | METHOD OF PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-07-01 | — | — | US | disclosed |
| US-7709651-B2 | asymmetriccomplex of copper(I) trifluoromethanesulfonate and 1,1-bis[2-[(4S)-(tert-butyl)-oxazoline]]cyclopropane is added to 3-methyl-2-butenyl acetate and ethyl diazoacetate using dichloroethane solvent to effect reaction to produce ethyl 3,3-dimethyl-2-(acetoxymethyl)cyclopropanecarboxylate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-05-04 | — | — | US | disclosed |
| US-20090048450-A1 | Process for production of optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1950208-A1 | PROCESS FOR PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE | Sumitomo Chemical Company, Limited (JP) | 2008-07-30 | — | — | EP | disclosed |
| US-20080027235-A1 | Method for Producing Optically Active Cyclopropanecarboxylate Compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2008-01-31 | — | — | US | disclosed |
| CN-101001826-A | Method for producing optically active cyclopropanecarboxylate compound | SUMITOMO CHEMICAL CO (JP) | 2007-07-18 | — | — | CN | disclosed |
| CN-1968958-A | Method for producing optically active cyclopropanecarboxylic ester compound | SUMITOMO CHEMICAL CO (JP) | 2007-05-23 | — | — | CN | disclosed |
| EP-1783111-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2007-05-09 | — | — | EP | disclosed |
| EP-1783130-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2007-05-09 | — | — | EP | disclosed |
| US-20070032659-A1 | Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-02-08 | — | — | US | disclosed |
| CN-1852887-A | Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same | SUMITOMO CHEMICAL CO (JP) | 2006-10-25 | — | — | CN | disclosed |
| EP-1674445-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND AND ASYMMETRIC COPPER COMPLEX FOR USE IN THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027235-A1 | Method for Producing Optically Active Cyclopropanecarboxylate Compound | ACSL6, AOC1, CA6 | TSHR 388/4885ALDH1A1 1222/4885LMNA 4253/4885 |
| US-20090048450-A1 | Process for production of optically active cyclopropanecarboxylate compound | CBR3, C9, CBR1 | TSHR 179/4885ALDH1A1 1594/4885LMNA 3700/4885 |
| US-20100168463-A1 | METHOD OF PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE | CYP1B1, HACL2, CMA1 | TSHR 2332/4885ALDH1A1 147/4885LMNA 2892/4885 |
| US-20070032659-A1 | Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same | CBR3, AOC3, CBR1 | TSHR 397/4885ALDH1A1 185/4885LMNA 4237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.