Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096077 | 0.78 | ALDH1A1 (0.47) | IDO1RAB9ANPC1TSHRCA1 | |
| SCHEMBL8551384 | 0.77 | CRHBP (0.53) | IDO1RAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL37665 | 0.75 | AKR1C3 (0.62) | IDO1AKR1C3RAB9ANPC1MAOB | |
| Bicarbonate SCHEMBL7693242 | 0.75 | IDO1 (0.59) | IDO1AKR1C3RAB9ANPC1LOXL2 | |
| SCHEMBL6046672 | 0.75 | RAB9A (0.54) | IDO1RAB9ANPC1CRHBPCRHR2 | |
| SCHEMBL3687614 | 0.74 | RAB9A (0.67) | IDO1AKR1C3RAB9ANPC1LOXL2 | |
| SCHEMBL31022840 | 0.74 | IDO1 (0.50) | IDO1AKR1C3RAB9ANPC1LOXL2 | |
| SCHEMBL6046632 | 0.74 | RAB9A (0.50) | IDO1AKR1C3RAB9ANPC1MAOB | |
| Hydrochloric Acid SCHEMBL11843534 | 0.73 | IDO1 (0.61) | IDO1AKR1C3RAB9ANPC1MAOB | |
| SCHEMBL1013 | 0.73 | IDO1 (0.62) | IDO1AKR1C3RAB9ALOXL2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516969-B | Targeted polylysine dendrimer therapeutic agent modified macromolecule 2 | STARPHARMA PTY LTD | 2013-07-03 | — | — | CN | disclosed |
| CN-101631818-B | Polylysine dendrimer contrast agent imaging macromolecule | STARPHARMA PTY LTD | 2013-02-06 | — | — | CN | disclosed |
| CN-101631818-A | Polylysine dendrimer contrast agent | STARPHARMA PTY LTD | 2010-01-20 | — | — | CN | disclosed |
| CN-101516969-A | Targeted polylysine dendrimer therapeutic agent | STARPHARMA PTY LTD (AU) | 2009-08-26 | — | — | CN | disclosed |