Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 2/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152866 | 0.86 | ALDH1A1 (0.52) | ALDH1A1LMNATDP1 | |
| SCHEMBL27870496 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNATDP1 | |
| SCHEMBL6046632 | 0.84 | RAB9A (0.50) | RAB9ANPC1ALDH1A1IDO1 | |
| SCHEMBL7367394 | 0.82 | CRHBP (0.58) | RAB9ACRHBPCRHR2NPC1ALDH1A1 | |
| SCHEMBL18045538 | 0.81 | CRHBP (0.56) | RAB9ACRHBPCRHR2NPC1ALDH1A1 | |
| SCHEMBL8716892 | 0.80 | RAB9A (0.61) | RAB9ACRHBPCRHR2NPC1ALDH1A1 | |
| SCHEMBL6151831 | 0.80 | RAB9A (0.61) | RAB9ACRHBPCRHR2NPC1ALDH1A1 | |
| SCHEMBL6645015 | 0.80 | RAB9A (0.61) | RAB9ACRHBPCRHR2NPC1ALDH1A1 | |
| SCHEMBL27448293 | 0.80 | CRHBP (0.57) | RAB9ACRHBPCRHR2NPC1ALDH1A1 | |
| SCHEMBL6469427 | 0.79 | HTR2A (0.51) | RAB9AALDH1A1SMN1; SMN2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060281686-A1 | Aza-peptides | LABORATOIRES SERONO SA (CH) | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281686-A1 | Aza-peptides | APP, APBA1, IAPP | RAB9A 3494/4885CRHBP 340/4885CRHR2 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.