SCHEMBL27753296

SCHEMBL27753296

O=C(NC1(C(=O)O)CCCCC1)c1cc2ccccc2o1.c1ccc2c(c1)ccc1c3c(ccc12)CCCC3

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.47
SMN1; SMN2 Q16637 5/20 0.47
NPC1 O15118 4/20 0.47
NFKB1 P19838 2/20 0.47
NFKB2 Q00653 2/20 0.47
RELA Q04206 2/20 0.47
LMNA P02545 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
BCHE P06276 6/20 0.42
ACHE P22303 6/20 0.42
TACR2 P21452 2/20 0.41
HPGD P15428 3/20 0.40
TP53 P04637 3/20 0.40
ALDH1A1 P00352 1/20 0.40
CXCR5 P32302 1/20 0.39
PKM P14618 1/20 0.39
GALK1 P51570 1/20 0.39
CXCR2 P25025 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1840233 0.83 RAB9A (0.55) RAB9ASMN1; SMN2NPC1NFKB1NFKB2
SCHEMBL28056171 0.73 HPGD (0.47) RAB9ANPC1NFKB1NFKB2RELA
Bicarbonate SCHEMBL27702695 0.73 HPRT1 (0.45) ACHEHPGDALDH1A1MAPT
SCHEMBL5097751 0.72 RAB9A (0.50) RAB9ASMN1; SMN2NPC1NFKB1NFKB2
Dibenzofuran SCHEMBL27564005 0.70 HPRT1 (0.42) ACHEHPGDALDH1A1KDM4EMEN1
Acetic Acid SCHEMBL27295805 0.70 ALDH1A1 (0.46) LMNAACHEHPGDALDH1A1KDM4E
SCHEMBL27508487 0.70 HPRT1 (0.45) ACHEHPGDALDH1A1MAPTHSD17B10
SCHEMBL4660547 0.70 HPRT1 (0.52) ACHEALDH1A1MAPTHSD17B10
Cyclopropane SCHEMBL27527638 0.70 HPRT1 (0.52) ACHEALDH1A1MAPTHSD17B10
Benzene SCHEMBL27260397 0.70 HPRT1 (0.52) ACHEALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101370773-B Cycloalkanecarboxamide derivative and method for producing same SEIKAGAKU KOGYO CO LTD 2014-04-09 CN disclosed
CN-101370773-A Cycloalkanecarboxamide derivative and method for producing same SEIKAGAKU KOGYO CO LTD (JP) 2009-02-18 CN disclosed