Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4643523 | 0.78 | MEN1 (0.45) | ALOX5MEN1KMT2AFOLH1FFAR4 | |
| SCHEMBL6079992 | 0.73 | APP (0.50) | FOLH1L3MBTL1MAPK1FFAR4FFAR1 | |
| SCHEMBL11085556 | 0.73 | KDM4E (0.50) | MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL16300892 | 0.72 | APP (0.46) | FOLH1L3MBTL1MAPK1FFAR4FFAR1 | |
| SCHEMBL10410151 | 0.71 | ALOX5 (0.52) | ALOX5FOLH1FFAR4LTB4RLTB4R2 | |
| SCHEMBL5783643 | 0.71 | APP (0.47) | KMT2AFOLH1L3MBTL1MAPK1FFAR4 | |
| SCHEMBL8057639 | 0.70 | LMNA (0.52) | MEN1KMT2AFOLH1L3MBTL1ALDH1A1 | |
| Acetic Acid SCHEMBL9653704 | 0.70 | SMN1; SMN2 (0.52) | FOLH1L3MBTL1ALDH1A1CYP2C19FFAR4 | |
| SCHEMBL10409146 | 0.69 | APP (0.49) | L3MBTL1FFAR4FFAR1APP | |
| SCHEMBL2009073 | 0.69 | CREBBP (0.66) | MEN1KMT2AL3MBTL1ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101321743-A | 1,1, 3-trioxo-1, 2, 5-thiadiazolidines as PTP-enzyme inhibitors and their use | NOVARTIS AG (CH) | 2008-12-10 | — | — | CN | disclosed |