Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009073 | 0.81 | CREBBP (0.66) | KDM4EKMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL14610914 | 0.80 | SLC1A5 (0.44) | KMT2AMEN1L3MBTL1HPGDALDH1A1 | |
| SCHEMBL11088305 | 0.80 | CRHBP (0.59) | KMT2AMEN1TSHRCRHBPCRHR2 | |
| SCHEMBL11088894 | 0.80 | KMT2A (0.57) | KMT2AHPGDALDH1A1HDAC1HDAC8 | |
| SCHEMBL4643523 | 0.80 | MEN1 (0.45) | KDM4EKMT2AMEN1EGFRSRC | |
| SCHEMBL27396917 | 0.78 | SMN1; SMN2 (0.71) | KDM4EKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL15754863 | 0.78 | HPGD (0.58) | KDM4EKMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL28979208 | 0.78 | NPC1 (0.53) | KDM4EKMT2AMEN1L3MBTL1HPGD | |
| SCHEMBL14610641 | 0.77 | TRPM8 (0.61) | KDM4EKMT2AMEN1TSHRHPGD | |
| SCHEMBL14610911 | 0.77 | TRPM8 (0.47) | BRD4LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457872-A | IMMUNOREGULATORY | Yamanouchi Pharmaceutical Co. (JP) | 1984-07-03 | — | — | US | disclosed |
| EP-0030436-B1 | 2-HYDROXYOXANILIC ACID DERIVATIVES AND SALTS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1984-05-09 | — | — | EP | disclosed |
| EP-0030436-A1 | 2-Hydroxyoxanilic acid derivatives and salts, their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-06-17 | — | — | EP | disclosed |