Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27755474 | 1.00 | EPHX1 (0.32) | EPHX1SLC6A2ADRA1AHTR2BSLC6A3 | |
| SCHEMBL27776054 | 0.84 | EPHX1 (0.31) | EPHX1THRB | |
| SCHEMBL27776072 | 0.84 | EPHX1 (0.31) | EPHX1THRB | |
| SCHEMBL9549207 | 0.80 | EPHX1 (0.34) | EPHX1THRBALDH1A1 | |
| SCHEMBL4803104 | 0.72 | THRB (0.37) | THRBALDH1A1 | |
| SCHEMBL18980967 | 0.71 | SLC6A2 (0.34) | EPHX1SLC6A2SLC6A3THRBALDH1A1 | |
| SCHEMBL24298445 | 0.70 | DNM1 (0.37) | EPHX1ALDH1A1 | |
| SCHEMBL15560285 | 0.70 | THRB (0.42) | EPHX1THRBALDH1A1 | |
| SCHEMBL7060090 | 0.69 | OPRM1 (0.31) | EPHX1 | |
| SCHEMBL27658433 | 0.69 | SLC6A2 (0.35) | SLC6A2SLC6A3THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101528225-B | 2-aminobenzoxazole carboxamides as 5HT3 modulators | ALBANY MOLECULAR RES INC | 2013-07-17 | — | — | CN | disclosed |
| CN-101528225-A | 2-aminobenzoxazole carboxamides as 5HT3 modulators | AMR TECHNOLOGY INC (US) | 2009-09-09 | — | — | CN | disclosed |