Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628157 | 0.88 | LTB4R2 (0.56) | PTGESALOX5LTB4R2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4315970 | 0.88 | PTGES (0.54) | PTGESALOX5LTB4R2MEN1KMT2A | |
| SCHEMBL20401146 | 0.87 | PTGES (0.48) | PTGESALOX5LTB4R2ALDH1A1MEN1 | |
| SCHEMBL2643233 | 0.87 | PTGES (0.63) | PTGESALOX5NR4A2LTB4R2 | |
| SCHEMBL13064402 | 0.85 | TP53 (0.51) | BCL2A1CNR2LTB4R2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2599998 | 0.84 | BCL2A1 (0.47) | BCL2A1CNR2LTB4R2PDK2PDK4 | |
| SCHEMBL2654384 | 0.80 | STAT3 (0.52) | PTGESALOX5STAT3 | |
| SCHEMBL12719411 | 0.79 | ALDH1A1 (0.42) | PTGESALOX5LTB4R2ALDH1A1MEN1 | |
| SCHEMBL13065224 | 0.79 | LMNA (0.53) | LTB4R2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL266144 | 0.78 | MT-CO2 (0.46) | BCL2A1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |