Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771612 | 0.88 | GRIA1 (0.38) | PRKCZMAPTALDH1A1NR3C2GRIA1 | |
| SCHEMBL27580466 | 0.88 | PRKCZ (0.35) | PRKCZMAPTALDH1A1GRIA1GRIA3 | |
| SCHEMBL27598051 | 0.88 | NPSR1 (0.40) | NPSR1TDP1ABL1BCRPRKCZ | |
| SCHEMBL27755584 | 0.85 | PDE5A (0.40) | NPSR1MAPTALDH1A1NR3C2KMT2A | |
| SCHEMBL27598121 | 0.84 | PIK3CD (0.37) | ABL1BCRPIK3CDPRKCZMAPT | |
| SCHEMBL27755573 | 0.84 | GRM5 (0.33) | PIK3CDPRKCZNR3C2GRIA1GRIA3 | |
| SCHEMBL27735013 | 0.83 | PDE10A (0.37) | ALDH1A1GAA | |
| SCHEMBL27735035 | 0.82 | GRIA1 (0.38) | PRKCZNR3C2GRIA1GRIA3PDE4D | |
| SCHEMBL27755568 | 0.82 | GRM5 (0.34) | PRKCZALDH1A1NR3C2NPC1GRIA1 | |
| SCHEMBL27734999 | 0.81 | PRKCZ (0.34) | PRKCZMAPTALDH1A1NR3C2GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101486683-B | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | Sanitary Material R&D Management Co.,Ltd. (JP) | 2011-12-21 | — | — | CN | disclosed |
| CN-101486683-A | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI R&D MAN CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |
| CN-100473647-C | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI CO LTD (JP) | 2009-04-01 | — | — | CN | disclosed |