Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27755568 | 0.88 | GRM5 (0.34) | PRKCZGRM5UCHL1NR3C2GHSR | |
| SCHEMBL27771612 | 0.88 | GRIA1 (0.38) | PRKCZGRM5UCHL1NR3C2GHSR | |
| SCHEMBL27755571 | 0.86 | GRM5 (0.33) | PRKCZGRM5UCHL1NR3C2GRIA1 | |
| SCHEMBL27735037 | 0.86 | PRKCZ (0.35) | PRKCZGAAHTT | |
| SCHEMBL27735035 | 0.86 | GRIA1 (0.38) | PRKCZGRM5UCHL1NR3C2GHSR | |
| SCHEMBL27755573 | 0.83 | GRM5 (0.33) | PRKCZGRM5UCHL1NR3C2GRIA1 | |
| SCHEMBL27735021 | 0.83 | ALDH1A1 (0.33) | PRKCZGRM5NR3C2GHSRGRIA1 | |
| SCHEMBL27580466 | 0.82 | PRKCZ (0.35) | PRKCZGRM5UCHL1GRIA1GRIA3 | |
| SCHEMBL27755572 | 0.81 | NPSR1 (0.39) | PRKCZNR3C2GRIA1GRIA3PDE4D | |
| SCHEMBL27735036 | 0.78 | KMT2A (0.42) | PRKCZGAAMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101486683-B | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | Sanitary Material R&D Management Co.,Ltd. (JP) | 2011-12-21 | — | — | CN | disclosed |
| CN-101486683-A | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI R&D MAN CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |
| CN-100473647-C | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI CO LTD (JP) | 2009-04-01 | — | — | CN | disclosed |