Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27771317 | 0.74 | NISCH (0.41) | NISCHGAATSHRCHRNB4CHRNA3 | |
| Biphenyl SCHEMBL29191183 | 0.74 | CRBN (0.67) | NISCHGAATSHRNPC1KDM4E | |
| Biphenyl SCHEMBL27458506 | 0.74 | NISCH (0.41) | NISCHGAATSHRCHRNB4CHRNA3 | |
| Biphenyl SCHEMBL29170957 | 0.74 | CRBN (0.67) | NISCHGAATSHRNPC1KDM4E | |
| Biphenyl SCHEMBL27457143 | 0.72 | NISCH (0.40) | NISCHGAATSHRCHRNB4CHRNA3 | |
| Biphenyl SCHEMBL11216763 | 0.72 | CRBN (0.64) | NISCHGAATSHRNPC1KDM4E | |
| SCHEMBL4825349 | 0.71 | KDM4E (0.48) | NISCHTSHRNPC1KDM4EMAPT | |
| SCHEMBL29030288 | 0.70 | FKBP5 (0.59) | NISCHGAATSHRNPC1KDM4E | |
| SCHEMBL28612537 | 0.70 | HTR2C (0.47) | CHRNB4CHRNA3HTR2CPARP10PARP11 | |
| Biphenyl SCHEMBL3453455 | 0.67 | ALDH1A1 (0.53) | NISCHGAATSHRSIGMAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101555264-B | Derivative of highly active tetra cyclic anthroquinones antibiotics and preparation and application thereof | TIANJIN HEMAY BIO TECH CO LTD | 2014-09-03 | — | — | CN | disclosed |
| CN-101555264-A | Derivative of highly active tetra cyclic anthroquinones antibiotics and preparation and application thereof | TIANJIN HEMEI BIO TECH CO LTD (CN) | 2009-10-14 | — | — | CN | disclosed |