Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | GRM8 | O00222 | 4/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.49 |
| ▸ | GRM6 | O15303 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL27760108 | 1.00 | GSR (0.54) | GSRMMP2GRM8GRM4GRM6 | |
| Lysine SCHEMBL28385610 | 0.99 | GSR (0.56) | GSRMMP2GRM8GRM4GRM6 | |
| Lysine SCHEMBL28327845 | 0.99 | GSR (0.56) | GSRMMP2GRM8GRM4GRM6 | |
| Lysine SCHEMBL11017422 | 0.85 | MMP2 (0.44) | GSRMMP2GRM8GRM4GRM6 | |
| Lysine SCHEMBL28734094 | 0.84 | MMP2 (0.43) | GSRMMP2GRM8GRM4GRM6 | |
| Lysine SCHEMBL22394602 | 0.84 | MMP2 (0.54) | GSRMMP2GRM8GRM4GRM6 | |
| Lysine SCHEMBL7792526 | 0.83 | GSR (0.50) | GSRMMP2GRM8GRM4GRM6 | |
| Dinitrophenylene SCHEMBL28977791 | 0.82 | KMO (0.58) | GSRMMP2GRM8GRM4GRM6 | |
| Glutamic Acid SCHEMBL3126271 | 0.82 | GRM8 (0.53) | GSRGRM8GRM4GRM6ALDH1A1 | |
| Glutamic Acid SCHEMBL29088693 | 0.81 | GRM8 (0.51) | GSRGRM8GRM4GRM6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116656655-A | Aminopeptidase and coding gene thereof | 江苏御娘食品有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-107400666-B | A kind of aminopeptidase and its encoding gene and application | 广东轻工职业技术学院 | 2019-11-22 | — | — | CN | disclosed |
| CN-107400666-A | A kind of aminopeptidase and its encoding gene and application | 广东轻工职业技术学院 | 2017-11-28 | — | — | CN | disclosed |
| CN-101560479-B | Low-temperature alkaline protease, application of low-temperature alkaline protease in aspect of detergents and protease producing bacteria | NANJING UNIVERSITY OF TECHNOLOGY | 2011-02-16 | — | — | CN | disclosed |
| CN-101560479-A | Low-temperature alkaline protease, application of low-temperature alkaline protease in aspect of detergents and protease producing bacteria | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2009-10-21 | — | — | CN | disclosed |