Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DPYD | Q12882 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103605 | 0.84 | GAA (0.44) | LMNAGAAL3MBTL1DPYDPOLB | |
| Acetic Acid SCHEMBL27871291 | 0.77 | POLB (0.51) | LMNAGAAL3MBTL1DPYDPOLB | |
| Thymine SCHEMBL6686289 | 0.76 | ATAD2 (0.58) | LMNAGAAL3MBTL1POLBKDM4E | |
| SCHEMBL1624884 | 0.75 | LMNA (0.42) | LMNAL3MBTL1POLBKDM4EALDH1A1 | |
| SCHEMBL1061623 | 0.74 | GAA (0.48) | LMNAGAADPYDALDH1A1SMN1; SMN2 | |
| SCHEMBL138381 | 0.73 | LMNA (0.46) | LMNAGAAPOLBKDM4EALDH1A1 | |
| SCHEMBL29100436 | 0.72 | ALDH1A1 (0.38) | LMNAGAADPYDKDM4EALDH1A1 | |
| Acetic Acid Methyl Ester SCHEMBL28329738 | 0.71 | POLB (0.52) | LMNAGAAPOLBKDM4EMAPT | |
| SCHEMBL29100434 | 0.71 | DPYD (0.47) | LMNAGAADPYDKDM4EALDH1A1 | |
| SCHEMBL7599612 | 0.70 | PARP1 (0.44) | LMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101426534-A | Methods and compositions for detecting and treating retinal diseases | GEORGE INANA (US) | 2009-05-06 | — | — | CN | disclosed |