Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.30 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27781997 | 0.83 | L3MBTL1 (0.33) | HCAR1SLC6A2SLC6A4 | |
| SCHEMBL27760504 | 0.71 | C5AR1 (0.32) | — | |
| SCHEMBL27760475 | 0.71 | SCN9A (0.34) | HCAR1SLC6A2SLC6A4SCN9ACHRM4 | |
| SCHEMBL27640356 | 0.65 | HCAR1 (0.41) | HCAR1SCN9A | |
| SCHEMBL74204 | 0.65 | HCAR1 (0.46) | HCAR1SLC6A2SLC6A4SCN9ACYP2D6 | |
| SCHEMBL4088183 | 0.65 | HCAR1 (0.39) | HCAR1SLC6A2SLC6A4SCN9A | |
| SCHEMBL27760467 | 0.65 | L3MBTL1 (0.35) | HCAR1CYP2D6 | |
| SCHEMBL2662469 | 0.63 | SLC6A2 (0.49) | SLC6A2SLC6A4CYP2D6KCNH2 | |
| SCHEMBL27624241 | 0.58 | KCNK3 (0.44) | SLC6A2SLC6A4CYP2D6KCNH2 | |
| SCHEMBL27306746 | 0.58 | DRD2 (0.44) | HCAR1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101553474-A | Imidazolidinone and imidazolidinone derivatives as 11 b-HSD 1 inhibitors for diabetes | HOFFMANN LA ROCHE (CH) | 2009-10-07 | — | — | CN | claimed |
| CN-101553474-A | Imidazolidinone and imidazolidinone derivatives as 11 b-HSD 1 inhibitors for diabetes | HOFFMANN LA ROCHE (CH) | 2009-10-07 | — | — | CN | disclosed |