Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27635322 | 0.83 | ACHE (0.40) | RAB9ANPC1MAPTACHEBCHE | |
| SCHEMBL5172865 | 0.82 | ALDH1A1 (0.47) | RAB9ANPC1MAPTACHEBCHE | |
| SCHEMBL4016329 | 0.81 | TDP1 (0.42) | RAB9ANPC1MAPTACHEBCHE | |
| SCHEMBL28032033 | 0.81 | ACHE (0.44) | RAB9ANPC1MAPTACHEBCHE | |
| SCHEMBL21351915 | 0.81 | ALDH1A1 (0.41) | RAB9ANPC1MAPTACHEBCHE | |
| SCHEMBL21352148 | 0.81 | ACHE (0.40) | RAB9ANPC1MAPTACHEBCHE | |
| SCHEMBL28766619 | 0.80 | ACHE (0.40) | RAB9ANPC1MAPTACHEBCHE | |
| SCHEMBL27548768 | 0.80 | CHRNA3 (0.43) | RAB9ANPC1MAPTACHEBCHE | |
| SCHEMBL29000949 | 0.79 | ACHE (0.42) | MAPTACHEBCHESMN1; SMN2MEN1 | |
| SCHEMBL27514766 | 0.78 | KMT2A (0.51) | RAB9ANPC1MAPTACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101506155-A | Biphenyl derivatives and their use in the treatment of hepatitis C | ARROW THERAPEUTICS LTD (GB) | 2009-08-12 | — | — | CN | disclosed |