Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775416 | 0.90 | FAAH (0.57) | FAAHCES1 | |
| SCHEMBL2775288 | 0.84 | FAAH (0.49) | FAAHCES1 | |
| SCHEMBL2776228 | 0.84 | FAAH (0.75) | FAAHCES1 | |
| SCHEMBL2771969 | 0.77 | FAAH (0.55) | FAAHCES1 | |
| SCHEMBL2772396 | 0.76 | FAAH (0.84) | FAAHCES1 | |
| SCHEMBL2775412 | 0.76 | FAAH (0.74) | FAAHCES1 | |
| SCHEMBL2774812 | 0.75 | FAAH (0.49) | FAAHCES1 | |
| SCHEMBL2774507 | 0.73 | CES1 (0.44) | FAAHCES1 | |
| SCHEMBL12472502 | 0.71 | FAAH (0.71) | FAAH | |
| SCHEMBL3711274 | 0.71 | MCL1 (0.55) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152082-A1 | TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008147553-A1 | TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-12-04 | — | — | WO | disclosed |