Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364607 | 0.89 | SCN9A (0.64) | SCN9AMAPT | |
| SCHEMBL1260197 | 0.88 | ALDH1A1 (0.52) | FAAHGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL25002929 | 0.87 | ADORA3 (0.52) | MCL1SCN9AFAAHCYP1A2GAA | |
| SCHEMBL3129022 | 0.85 | MCL1 (0.67) | MCL1SCN9A | |
| SCHEMBL3135694 | 0.84 | SCN9A (0.56) | MCL1SCN9A | |
| SCHEMBL13187819 | 0.83 | SCN9A (0.54) | MCL1SCN9A | |
| SCHEMBL3712561 | 0.83 | MCL1 (0.59) | MCL1FAAHSMN1; SMN2 | |
| SCHEMBL3126744 | 0.82 | SCN9A (0.59) | MCL1SCN9A | |
| SCHEMBL483444 | 0.82 | MAPT (0.56) | SCN9AFAAHCYP1A2GAAMAPT | |
| SCHEMBL25002893 | 0.82 | NPC1 (0.55) | SCN9AFAAHCYP1A2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1422254-A | Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof | EURO CELTIQUE SA (LU) | 2003-06-04 | — | — | CN | claimed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| CN-1422254-A | Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof | EURO CELTIQUE SA (LU) | 2003-06-04 | — | — | CN | disclosed |