Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | OGG1 | O15527 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306705 | 1.00 | TSHR (0.40) | TSHRP2RX3ALDH1A1KDM4EHPGD | |
| SCHEMBL1305135 | 0.92 | P2RX3 (0.46) | TSHRP2RX3ALDH1A1KDM4EHPGD | |
| SCHEMBL1306822 | 0.90 | TSHR (0.38) | TSHRP2RX3ALDH1A1KDM4EHPGD | |
| SCHEMBL1307997 | 0.84 | P2RX3 (0.62) | TSHRP2RX3ALDH1A1KDM4EHPGD | |
| SCHEMBL3821011 | 0.83 | TSHR (0.43) | TSHRP2RX3ALDH1A1KDM4EHPGD | |
| SCHEMBL1305881 | 0.81 | ALDH1A1 (0.41) | TSHRALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL1306812 | 0.78 | TSHR (0.39) | TSHRP2RX3ALDH1A1KDM4EHPGD | |
| SCHEMBL1306707 | 0.78 | P2RX3 (0.40) | P2RX3ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL3819048 | 0.76 | P2RX3 (0.48) | TSHRP2RX3ALDH1A1KDM4EHPGD | |
| SCHEMBL2895820 | 0.76 | P2RX3 (0.45) | TSHRP2RX3ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101573327-A | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RES INST CHEM TECH (KR) | 2009-11-04 | — | — | CN | disclosed |