Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 4/20 | 0.45 |
| ▸ | PARP1 | P09874 | 4/20 | 0.43 |
| ▸ | DDIT3 | P35638 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742896 | 0.91 | MMP2 (0.50) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL27763518 | 0.91 | MMP2 (0.50) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL27742883 | 0.91 | MMP2 (0.50) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL27763521 | 0.87 | MMP2 (0.53) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL27763527 | 0.86 | MMP2 (0.52) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL27742870 | 0.86 | MMP2 (0.52) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL27763507 | 0.86 | MMP2 (0.52) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL27742891 | 0.84 | DHODH (0.49) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL27742882 | 0.83 | DHODH (0.48) | MEN1KMT2ADHODHPARP1NPC1 | |
| SCHEMBL27742898 | 0.83 | MAPT (0.49) | MEN1KMT2ADHODHPARP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |