Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | MMP8 | P22894 | 3/20 | 0.50 |
| ▸ | MMP13 | P45452 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27763514 | 0.91 | MMP2 (0.56) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL27742883 | 0.90 | MMP2 (0.50) | MMP2MMP9MMP8MMP13RAB9A | |
| SCHEMBL27742896 | 0.90 | MMP2 (0.50) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL27763531 | 0.86 | ALDH1A1 (0.52) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL27742879 | 0.85 | NPC1 (0.49) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL27763510 | 0.85 | PARP1 (0.51) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL27763504 | 0.84 | NPC1 (0.50) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL27763521 | 0.83 | MMP2 (0.53) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL27742870 | 0.82 | MMP2 (0.52) | MMP2MMP9MMP8MMP13NPC1 | |
| SCHEMBL27763527 | 0.82 | MMP2 (0.52) | MMP2MMP9MMP8MMP13CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |