Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27763521 | 0.90 | MMP2 (0.53) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL27742870 | 0.89 | MMP2 (0.52) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL27763507 | 0.89 | MMP2 (0.52) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL27763514 | 0.86 | MMP2 (0.56) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL27742883 | 0.86 | MMP2 (0.50) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL27742873 | 0.84 | DHODH (0.49) | KMT2AMEN1DHODHPARP1CYP1A2 | |
| SCHEMBL27742876 | 0.84 | PARP1 (0.46) | DHODHPARP1CYP1A2HPGDCYP2C19 | |
| SCHEMBL27742896 | 0.82 | MMP2 (0.50) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL27763518 | 0.82 | MMP2 (0.50) | MMP2MMP9MMP8MMP13KMT2A | |
| SCHEMBL28780360 | 0.80 | PARP1 (0.47) | KMT2ADHODHPARP1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |