Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742870 | 0.90 | MMP2 (0.52) | MMP2MMP9MMP8MMP13TDP1 | |
| SCHEMBL27763507 | 0.90 | MMP2 (0.52) | MMP2MMP9MMP8MMP13TDP1 | |
| SCHEMBL27763527 | 0.90 | MMP2 (0.52) | MMP2MMP9MMP8MMP13TDP1 | |
| SCHEMBL27763514 | 0.87 | MMP2 (0.56) | MMP2MMP9MMP8MMP13PARP1 | |
| SCHEMBL27742897 | 0.84 | NPC1 (0.44) | PARP1NPC1LMNATP53GAA | |
| SCHEMBL27742883 | 0.83 | MMP2 (0.50) | MMP2MMP9MMP8MMP13PARP1 | |
| SCHEMBL27742896 | 0.83 | MMP2 (0.50) | MMP2MMP9MMP8MMP13L3MBTL1 | |
| SCHEMBL27763518 | 0.83 | MMP2 (0.50) | MMP2MMP9MMP8MMP13PARP1 | |
| SCHEMBL27763526 | 0.83 | KCNMA1 (0.50) | MMP2MMP9MMP8MMP13KCNMA1 | |
| SCHEMBL27742888 | 0.80 | KCNMA1 (0.47) | MMP2MMP9MMP8MMP13KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |