Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | LCLAT1 | Q6UWP7 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742874 | 0.90 | MAPT (0.51) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL27763598 | 0.89 | RAB9A (0.56) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL27742887 | 0.89 | MAPT (0.51) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL28780360 | 0.84 | PARP1 (0.47) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL27742878 | 0.84 | PARP1 (0.48) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL27763530 | 0.83 | PARP1 (0.47) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL27763519 | 0.83 | PARP1 (0.47) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL27742890 | 0.83 | MAPT (0.49) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL27742883 | 0.80 | MMP2 (0.50) | RAB9AMAPTSMN1; SMN2POLBPARP1 | |
| SCHEMBL27763525 | 0.80 | RAB9A (0.43) | RAB9ANPC1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |