Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | DHODH | Q02127 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LCLAT1 | Q6UWP7 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28780360 | 0.87 | PARP1 (0.47) | RAB9ADHODHALDH1A1NPC1TP53 | |
| SCHEMBL27742881 | 0.87 | MAPT (0.52) | RAB9ADHODHALDH1A1NPC1TP53 | |
| SCHEMBL27742874 | 0.84 | MAPT (0.51) | RAB9ADHODHALDH1A1NPC1TP53 | |
| SCHEMBL27763524 | 0.84 | DHODH (0.42) | DHODHALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL27763529 | 0.83 | DHODH (0.42) | DHODHALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL27742889 | 0.83 | DHODH (0.46) | DHODHALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL27742880 | 0.83 | DHODH (0.46) | DHODHALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL27742870 | 0.80 | MMP2 (0.52) | RAB9ADHODHALDH1A1NPC1MAPT | |
| SCHEMBL27763516 | 0.80 | RAB9A (0.51) | RAB9ADHODHALDH1A1NPC1TP53 | |
| SCHEMBL27763598 | 0.80 | RAB9A (0.56) | RAB9ADHODHALDH1A1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |