Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.48 |
| ▸ | PARP1 | P09874 | 8/20 | 0.44 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742871 | 0.90 | DHODH (0.44) | DHODHPARP1PKN1PKN2NR2E3 | |
| SCHEMBL27763513 | 0.90 | MMP2 (0.43) | DHODHPARP1PKN1PKN2NR2E3 | |
| SCHEMBL27742891 | 0.88 | DHODH (0.49) | DHODHPARP1PKN1PKN2GRM5 | |
| SCHEMBL28780427 | 0.87 | PARP1 (0.51) | DHODHPARP1TP53MAPTPOLB | |
| SCHEMBL27742898 | 0.87 | MAPT (0.49) | DHODHPARP1PKN1PKN2GRM5 | |
| SCHEMBL27742882 | 0.87 | DHODH (0.48) | DHODHPARP1PKN1PKN2GRM5 | |
| SCHEMBL27742877 | 0.87 | DHODH (0.48) | DHODHPARP1PKN1PKN2GRM5 | |
| SCHEMBL27742889 | 0.85 | DHODH (0.46) | DHODHPARP1PKN1PKN2MAPT | |
| SCHEMBL27763532 | 0.85 | PTGES (0.46) | DHODHPARP1PKN1PKN2TP53 | |
| SCHEMBL27763515 | 0.85 | DHODH (0.53) | DHODHPARP1PKN1PKN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |