Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | DHODH | Q02127 | 8/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27763528 | 0.90 | PARP1 (0.47) | PTGESPARP1DHODHARAKR1C3 | |
| SCHEMBL27742885 | 0.88 | PARP1 (0.46) | PTGESPARP1DHODHARAKR1C3 | |
| SCHEMBL27742889 | 0.88 | DHODH (0.46) | PTGESPARP1DHODHMAPTPKN1 | |
| SCHEMBL27763515 | 0.88 | DHODH (0.53) | PARP1DHODHAKR1C3TP53MAPT | |
| SCHEMBL27763520 | 0.85 | DHODH (0.48) | PARP1DHODHTP53MAPTPKN1 | |
| SCHEMBL27742871 | 0.84 | DHODH (0.44) | PTGESPARP1DHODHARAKR1C3 | |
| SCHEMBL27763507 | 0.84 | MMP2 (0.52) | PARP1DHODHMAPTHTTLMNA | |
| SCHEMBL27742876 | 0.84 | PARP1 (0.46) | PTGESPARP1DHODHARAKR1C3 | |
| SCHEMBL27763513 | 0.80 | MMP2 (0.43) | PARP1DHODHTP53MAPTPKN1 | |
| SCHEMBL27742873 | 0.80 | DHODH (0.49) | PTGESPARP1DHODHARAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |