Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 10/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27742880 | 0.89 | DHODH (0.46) | DHODHKMT2APKN1PKN2PARP1 | |
| SCHEMBL27763529 | 0.89 | DHODH (0.42) | DHODHKMT2APKN1PKN2PARP1 | |
| SCHEMBL27742889 | 0.89 | DHODH (0.46) | DHODHKMT2APKN1PKN2PARP1 | |
| SCHEMBL27763523 | 0.88 | MAPT (0.51) | DHODHPKN1PKN2PARP1KDM4E | |
| SCHEMBL27742870 | 0.85 | MMP2 (0.52) | DHODHKMT2APKN1PKN2PARP1 | |
| SCHEMBL27742891 | 0.85 | DHODH (0.49) | DHODHKMT2APKN1PKN2PARP1 | |
| SCHEMBL27763525 | 0.84 | RAB9A (0.43) | DHODHKMT2APKN1PKN2PARP1 | |
| SCHEMBL27763508 | 0.84 | MMP2 (0.44) | DHODHKMT2APKN1PKN2PARP1 | |
| SCHEMBL27763526 | 0.84 | KCNMA1 (0.50) | KMT2APKN1PKN2PARP1MEN1 | |
| SCHEMBL27742897 | 0.83 | NPC1 (0.44) | DHODHKMT2APKN1PKN2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |