Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | DHODH | Q02127 | 10/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27763529 | 0.90 | DHODH (0.42) | PARP1DHODHMAPTPKN1PKN2 | |
| SCHEMBL27763532 | 0.90 | PTGES (0.46) | PARP1DHODHTP53MAPTAR | |
| SCHEMBL27742885 | 0.90 | PARP1 (0.46) | PARP1DHODHTP53MAPTAR | |
| SCHEMBL27742876 | 0.90 | PARP1 (0.46) | PARP1DHODHARAKR1C3PKN1 | |
| SCHEMBL27742877 | 0.87 | DHODH (0.48) | PARP1DHODHTP53MAPTPKN1 | |
| SCHEMBL27742888 | 0.86 | KCNMA1 (0.47) | PARP1HTTPKN1PKN2NPC1 | |
| SCHEMBL27763507 | 0.86 | MMP2 (0.52) | PARP1DHODHMAPTHTTLMNA | |
| SCHEMBL27742886 | 0.83 | PARP1 (0.47) | PARP1DHODHTP53MAPTPKN1 | |
| SCHEMBL27763519 | 0.82 | PARP1 (0.47) | PARP1DHODHTP53MAPTAKR1C3 | |
| SCHEMBL27742892 | 0.82 | MMP2 (0.43) | PARP1DHODHTP53MAPTPKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |