SCHEMBL277642

SCHEMBL277642

CCOCCN1C(=O)C=CC1=O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 11/20 0.72
FAAH O00519 4/20 0.50
PTGS1 P23219 3/20 0.50
PTGS2 P35354 3/20 0.50
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
BLM P54132 2/20 0.50
GMNN O75496 1/20 0.50
THPO P40225 1/20 0.50
PMP22 Q01453 1/20 0.50
HPGD P15428 2/20 0.48
HSP90AA1 P07900 2/20 0.48
TLR9 Q9NR96 1/20 0.48
TP53 P04637 1/20 0.48
PKM P14618 1/20 0.48
XBP1 P17861 1/20 0.48
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21014255 0.96 MGLL (0.80) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL15065220 0.96 MGLL (0.80) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL31633417 0.96 MGLL (0.80) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL4761624 0.88 MGLL (0.58) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL407969 0.86 MGLL (0.95) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL4761635 0.86 MGLL (0.61) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL753123 0.85 MGLL (0.76) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL4761628 0.84 MGLL (0.63) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL15082420 0.84 MGLL (1.00) MGLLFAAHPTGS1PTGS2ALDH1A1
SCHEMBL140275 0.84 MGLL (1.00) MGLLFAAHPTGS1PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903035-A Maleimide resin, process for producing the same, 3D-printable maleimide resin composition, process for producing the same, and device produced therefrom 上海信斯帝克新材料有限公司 2024-04-19 CN claimed
CN-113717455-A Resin composition, thermoplastic resin composite material, and thermoplastic resin article 中国石油化工股份有限公司 2021-11-30 CN claimed
CN-107106450-B Shaping keratin fibres using arabinose and ethylene carbonate 宝洁公司 2020-12-01 CN claimed
US-12514926-B2 Splicing modulator antibody-drug conjugates and methods of use EISAI R&D MANAGEMENT CO., LTD. (JP) 2026-01-06 US disclosed
US-12514928-B2 Herboxidiene antibody-drug conjugates and methods of use EISAI R&D MANAGEMENT CO., LTD. (JP) 2026-01-06 US disclosed
US-20250135017-A1 SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-05-01 US disclosed
US-12172986-B2 Splicing modulator antibody-drug conjugates and methods of use EISAI R&D MANAGEMENT CO., LTD (JP) 2024-12-24 US disclosed
US-20240360108-A1 SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-10-31 US disclosed
CN-117903035-A Maleimide resin, process for producing the same, 3D-printable maleimide resin composition, process for producing the same, and device produced therefrom 上海信斯帝克新材料有限公司 2024-04-19 CN disclosed
US-11945807-B2 Splicing modulator antibody-drug conjugates and methods of use EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-04-02 US disclosed
CN-113717455-B Resin composition, thermoplastic resin composite material, and thermoplastic resin article 中国石油化工股份有限公司 2023-12-29 CN disclosed
US-20090280550-A1 Polymer-Factor IX Moiety Conjugates NEKTAR THERAPEUTICS AL, CORPORATION (US) 2009-11-12 US disclosed
US-7579444-B2 Polymer-factor IX moiety conjugates NEKTAR THERAPEUTICS AL, CORPORATION (US) 2009-08-25 US disclosed
US-20090041714-A1 Binding element comprising polyethylene glycol and antihemophilic factor for use in treatment of hemophilia NEKTAR THERAPEUTICS AL, CORPORATION (US) 2009-02-12 US disclosed
US-20090012241-A1 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS AL, CORPORATION (US) 2009-01-08 US disclosed
US-7432331-B2 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS AL, CORPORATION (US) 2008-10-07 US disclosed
US-7432330-B2 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS AL, CORPORATION (US) 2008-10-07 US disclosed
US-20080058504-A1 Water soluble polyoxyethylene glylcol polyvinylpyrrolidone, polyvinyl alcohol, polyoxazoline, and/or polyacryloylmorpholine, conjugated to antihemophilic factor NEKTAR THERAPEUTICS 2008-03-06 US disclosed
US-20070092482-A1 Conjugates of a G-CSF moiety and a polymer NEKTAR THERAPEUTICS 2007-04-26 US disclosed
US-7199223-B2 Water soluble polyoxyethylene glylcol polyvinylpyrrolidone, polyvinyl alcohol, polyoxazoline, and/or polyacryloylmorpholine, conjugated to antihemophilic factor NEKTAR THERAPEUTICS AL, CORPORATION (US) 2007-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360108-A1 SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE RBM17, RBM22, SF3B1 MGLL 4600/4885FAAH 4427/4885PTGS1 3783/4885
US-20090041714-A1 Binding element comprising polyethylene glycol and antihemophilic factor for use in treatment of hemophilia F13B, F8, F13A1 MGLL 3265/4885FAAH 3529/4885PTGS1 2931/4885
US-11945807-B2 Splicing modulator antibody-drug conjugates and methods of use RBM17, RBM22, SF3B1 MGLL 4600/4885FAAH 4427/4885PTGS1 3783/4885
US-20070092482-A1 Conjugates of a G-CSF moiety and a polymer CSF3R, GMFG, CSF1R MGLL 1573/4885FAAH 3126/4885PTGS1 1536/4885
US-20080058504-A1 Water soluble polyoxyethylene glylcol polyvinylpyrrolidone, polyvinyl alcohol, polyoxazoline, and/or polyacryloylmorpholine, conjugated to antihemophilic factor F8, F13A1, F13B MGLL 544/4885FAAH 1570/4885PTGS1 1789/4885
US-12172986-B2 Splicing modulator antibody-drug conjugates and methods of use RBM17, RBM22, SF3B1 MGLL 4600/4885FAAH 4427/4885PTGS1 3783/4885
US-20250135017-A1 SPLICING MODULATOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE RBM17, SNRPE, HNRNPAB MGLL 4708/4885FAAH 4513/4885PTGS1 4300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.