Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 15/20 | 0.53 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.49 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14134780 | 1.00 | ADK (0.53) | ADKHASPINDOT1LRAB9AMTOR | |
| SCHEMBL27786173 | 0.88 | ADK (0.48) | ADKDOT1LRAB9APRMT5WDR77 | |
| SCHEMBL27764457 | 0.88 | ADK (0.58) | ADKDOT1LSLC29A1 | |
| SCHEMBL12154911 | 0.88 | ADK (0.48) | ADKDOT1LRAB9APRMT5WDR77 | |
| SCHEMBL27786170 | 0.88 | ADK (0.63) | ADKHASPINDOT1LRAB9APRMT5 | |
| SCHEMBL14134806 | 0.85 | ADK (0.41) | ADKDOT1LSLC29A1 | |
| SCHEMBL13068771 | 0.85 | ADK (0.61) | ADKHASPINDOT1LRAB9AMTOR | |
| SCHEMBL20419264 | 0.85 | ADK (0.61) | ADKHASPINDOT1LRAB9AMTOR | |
| SCHEMBL3768787 | 0.85 | ADK (0.61) | ADKHASPINDOT1LRAB9AMTOR | |
| SCHEMBL29363011 | 0.84 | ADK (0.55) | ADKHASPINDOT1LRAB9AMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101600726-A | The novel nucleoside analogs that is used for the treatment of virus infection | NOVARTIS AG (CH) | 2009-12-09 | — | — | CN | disclosed |