Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 12/20 | 0.63 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.63 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | PAK4 | O96013 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | FLT1 | P17948 | 1/20 | 0.53 |
| ▸ | LTK | P29376 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20938191 | 0.88 | ADK (0.67) | ADKDOT1LDAPK3MAP4K4PAK4 | |
| SCHEMBL12154911 | 0.88 | ADK (0.48) | ADKDOT1LPRMT5WDR77NPC1 | |
| SCHEMBL27764443 | 0.88 | ADK (0.53) | ADKDOT1LPRMT5WDR77HASPIN | |
| SCHEMBL27786173 | 0.88 | ADK (0.48) | ADKDOT1LPRMT5WDR77NPC1 | |
| SCHEMBL14134780 | 0.88 | ADK (0.53) | ADKDOT1LPRMT5WDR77HASPIN | |
| SCHEMBL18672066 | 0.80 | AHCY (0.57) | DOT1L | |
| SCHEMBL27764503 | 0.79 | ADK (0.51) | ADKPRMT5WDR77METTL3 | |
| SCHEMBL1738494 | 0.78 | ADK (0.61) | ADKDOT1LFLT3CDK5PRMT5 | |
| SCHEMBL6732487 | 0.78 | ADK (0.61) | ADKDOT1LFLT3CDK5PRMT5 | |
| SCHEMBL16978197 | 0.78 | ADK (1.00) | ADKDOT1LPRMT5WDR77TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101600726-A | The novel nucleoside analogs that is used for the treatment of virus infection | NOVARTIS AG (CH) | 2009-12-09 | — | — | CN | disclosed |